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Binding to Arg70 obviated the requirement for binding into the ATP Hinge region.
Plexins contain an extracellular domain that binds semaphorin, and a large domain inside the cell that can turn semaphorin binding into cellular responses.
We have engineered calcium-ion binding into the LH1 antenna of Rba.
A transducer then converts the number of complex molecular structures that are formed due to the binding into a signal.
Both 1 and 5 competitively inhibited the ATP binding into its pocket in the c-MET catalytic domain.
We present a case study of serine protease inhibitors with a bis phenyl)methane moiety binding into the S3 pocket.
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The last decade studies about biosensors have proposed various high sensitive ways to convert bimolecular bindings into electrical and optical signals [30, 31, 32, 33].
The RanGTP gradient model (Görlich et al, 1996; Izaurralde et al, 1997) provides an explanation for the directionality of the corresponding transport pathways: Importins recruit cargo at low RanGTP levels in the cytoplasm, release their cargo upon RanGTP-binding into the nucleus, and return RanGTP-bound to the cytoplasm.
Docking study was also performed to provide an insight about the binding mode into binding sites of topoisomerase enzyme.
Docking study was also performed to provide an insight about the binding mode into binding sites of DPP-4 enzyme.
Molecular docking study was performed using Maestro 9.0 (Schrodinger Inc. USA) to provide binding mode into binding sites of CDK2.
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