Exact(1)
Through a subtle binding interplay between Arb, lipids, viral and cellular proteins, Arb might efficiently block HCV entry and membrane fusion interacting with the main actors of the early steps of viral entry.
Similar(59)
In this review we will focus on the various aspects of PML RAR α functioning with respect to its genome-wide binding spectrum, its interplay with RXR and its regulation of various epigenetic modifications.
Visual object binding requires a cognitive interplay between perception, memory, and response.
Finally, the interplay between binding efficiency and therapeutic efficacy for optimizing natural products, random hits, and fragments is discussed.
We further dissected GATA2MP binding according to TF interplay and DNA motif content.
The aggregation characteristics of α-synuclein appear to be dependent on the conformational state of the monomeric protein; 10 thus, the complex interplay between binding and folding is directly relevant to the disease aspects of the protein.
To test whether the steady-state distribution of rproteins in the nucleus reflects the interplay between binding to rRNA in the nucleolus and degradation by the proteasome in the nucleoplasm, we compared the effect of proteasome inhibitors on the nuclear distribution of rproteins in cells with or without prior inhibition of rRNA synthesis.
Herein we present a study of the interplay between ligand binding and motions of the C-loop capping the binding site.
More significantly, our results indicate that the interplay between multivalent binding and shear force can reproduce the shear-enhanced binding phenomenon, which suggests that under certain conditions, this phenomenon can also occur in systems that do not show a catch-bond behavior.
This suggests a mode of GATA factor interplay whereby GATA2 binding in MPCs persists in E cells and acts as a "pioneer" for binding of GATA1 to a second GATA motif.
For example, synergy may effectively modulate binding kinetics, balance the delicate interplay between enthalpy and entropy by using the funneled energy landscape more efficiently, thus yielding high specificity with carefully balanced free energy of binding.
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