Sentence examples for binding interface with the from inspiring English sources

Above comparisons of the BV binding interface with the other three GI NoV emphasize the conservation of the CBP and the variations of the other binding sites, two features that may confer NoVs both viability and adaptability (see Discussion).

Each Puf repeat is organized into three α-helices, the second of which provides a binding interface with the target RNA.

The binding interface with the distal Ub covers 1,045 Å and involves the Ile44 patch that interacts with a helical arm (aa 254 264) conserved in all OTU domains.

The Python bindings interface with the PyQt python bindings for the Qt toolkit, which enables Python code to use all of Qt's features when writing a plugin.

The diversified loops contribute nearly 75% of the binding interface with each of the three loops making substantial contributions (91, 178, and 234 Å for the BC, DE, and FG loops, respectively).

Previous studies have suggested that CNM-related mutations in the SH3 domain disrupt the binding interface with proline-rich sequences and interfere with the ability to recruit dynamin 2. In fact, cellular experiments showed that the colocalization of BIN1 C-terminal mutants and dynamin 2 were decreased relative to BIN1-FL.

The SCID mutations of IL-7Rα locate outside the binding interface with IL-7, suggesting that the expressed mutations cause protein folding defects in IL-7Rα.

This alteration affects the entire binding interface with ASV as reflected in the altered van der Waals interactions, while the inhibitor protease hydrogen bonding network is maintained (Supplementary Table S2).

Molecular dynamics simulation has revealed that the conformational microstates of the complex of Bcl-xl and ABT263 shows heterogeneity at the binding interface with Bcl-xl in contrast to the precise interactions witnessed in case of ABT737.

This is likely to be an underestimate of the reduction in affinity since the large differences in the limiting CSPs for residues in the fully bound state for the I424S mutant versus wild-type UBA are consistent with the mutant forming a much weaker binding interface with only a small set of the contacts observed for the wild-type UBA.

In ubiquitin, only 13% of the surface makes up the binding interface with MMS2.