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Thus, only two compounds might be sufficient to block most noroviruses in the two genogroups studied here, each group sharing a similar binding interface that could be blocked by one common inhibitor.
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He suggested a few small tweaks to Twitter's interface that could minimize cases of mistaken identity.
As a potent tumor suppressor with multiple intriguing domains, for example, the newly identified GBA and the Frizzled-binding domain, Daple presents many signaling interfaces that could be developed as targets for modulating Wnt signaling.
Companies are looking for new interfaces that could redefine who profits from mobile computing.
It has software -- its instant messaging technology and its AOL user interface -- that could pose a threat to Microsoft Windows.
Imagine what an interface like that could do for live video streams?
The p110αEEE545K/p85α Cdc42-binding interface may rep110αEEE545K/p85α Cdc42-bindingat could interfaceI3Kα E545K signalling without affecting wild-type PI3Kα signalling in non-tumayrepresent
53 Can protein protein interfaces be predicted from the structures of their components, or, in other words, are there specific chemical and physical characteristics on a protein protein interface that we could use to predict protein-binding sites on a protein surface?
This is largely because they involve shallow and extensive interfaces with no features that could support effective small molecule binding.
TCR cross-reactivity fits well with the observation that receptor binding occurs with conformational shifts in the CDR loops, as plasticity or adaptability in the binding interface could broaden the reactivity of any given receptor.
The TBCC αβ-tubulin binding interface ensures that catalysis is activated more efficiently upon αβ-tubulin binding to TBC-DEG.
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