Sentence examples for binding interface and this from inspiring English sources

The tripeptide motif LDV was identified as part of the α4β7 binding interface, and this motif appears in gp120 V2 and the liganded CH58 structure as LDI (gp120179 181) (Liao et al., 2013, Zeller et al., 2001).

We further characterized this interaction, narrowed down the binding interface, and demonstrated that Draxin competes with Netrin receptors for binding to Netrin-1.

The other residues in this community are close to the co-activator binding interface and also present in most human nuclear receptors.

Our experiments were designed to map the arrestin rhodopsin binding interface and use the distance and orientation constraints obtained from TrIQ measurements to model this interaction.

Open image in new window Figure 5 The S228P mutation weakened subunit binding interface and modified surface charge distributions.

The distinct binding interface and kinetics of durvalumab compared to the other therapeutic MAbs indicate the special anti-tumor efficacy and pharmacokinetics of this MAb.

The slowdown of the picosecond components reflects more rigid water networks at the binding interface and in the active site.

10.7554/eLife.10147.016 Figure 5. Evolution of the binding interface and hinge during the evolution of AncGKPID spindle orientation functions.

This model agonistic antibody was then used as a starting point for mutational and crystallographic studies to explore the binding interface and better understand the agonistic activity.

As noted in our previous study, the RPA32C binding interface is devoid of hydrophobic pockets typically found at protein binding interfaces and, rather, is relatively flat.

This study describes a new framework that utilizes experimental evidence on structural complexes, the atomic details of binding interfaces and evolutionary conservation to map the human protein interactome.