Sentence examples for binding interactions within the from inspiring English sources
This difference is explained through their binding interactions within the active site of the HIV-1 integrase intasome.
Total five molecules were retrieved with good docking scores and good binding interactions within the active site of WT and mutated ROS-1.
Biological membranes exhibit high permeability and high selectivity because they possess transmembrane proteins6 with well-defined channel pore sizes that synergistically combine size, charge, van der Waals, and specific binding interactions within the channels to enhance the transport of target species.
Nevertheless, the novel binding interactions within the C6H5(CH2)8 group may likely be critical for the future design of PBD-binding antagonists.
Studying the binding interactions within the nicotine receptor family might lead not only to new ways of helping people stop smoking, he says, but also to new treatments for illnesses such as Alzheimer's disease, autism, Parkinson's disease, and schizophrenia.
These compounds were scored based on their potential to utilize hydrophilic and hydrophobic binding interactions within the pocket that contained histidine 280 and aspartic acid 278, which are required for the proteolytic activity of ATG4B.
After years of biochemical and phylogenetic studies, the general global structure of the group II intron and several metal-binding interactions within the core of the ribozyme are becoming clearer, and recent crystal structures corroborate proposed mechanistic models of a multinuclear metal-based catalytic mechanism.
To our knowledge, the latter analysis has not been reported previously, nor has a role for human microRNA binding interactions within P. falciparum transcripts.
The binding pocket in CDK2 is not exposed to solvent and important hydrogen bonding interactions within the active site are of limited flexibility [82].
Crystal structures of the protease in complex with boundary substrates show that, outside the catalytic triad, the majority of the substrate binding interactions are within domain 2 of the protease, in particular within the S2 and S4 pockets, which interact with the P2 and P4 boundary residues, respectively [ 26, 28, 29].
Molecular modeling within the RARα binding pocket was used to compare binding interactions of the desfluoro analog to a known RAR antagonist.
