Sentence examples similar to binding interactions for small from inspiring English sources

Others are effected by cooperative binding interactions of small peptide elements within regulatory protein polypeptide chains.

Elucidating the binding interaction of small bioactive molecules with DNA provides a structural guideline for designing new drugs with improved selectivity and superior clinical efficacy.

BindingDB contains more than one million binding interactions for seven thousand protein targets and 495 thousand small molecules.

Considering that a hydrocarbon and a drug molecule could adopt the same shape, CT helps to identify molecules with similar 3-D orientation of features, e.g., necessary for making binding interactions between a small molecule and protein binding pocket.

1H NMR titration results revealed that the binding process includes two steps: (i) hydrogen bonding interactions (for small quantities of acetate) and (ii) proton transfer between the sensor 3 and the coordinated anion (for high quantities of acetate).

Of these, the experiments identified a total of 47 small-molecule/protein binding interactions with μM or better affinities.

In this work, a new structure-differential binding (SDB) method, combined with ESI-MS and molecular docking (MD) techniques (SDB ESIMS MD), was developed and applied to a study of the binding interactions in noncovalent protein small drug molecule complexes for the characterization of binding sites and binding modes.

(A) The binding interactions with selected residues of the active site for compound 4b.

SPR-MS is limited by its inability to measure small ligands conveniently, but advances in life sciences allow more and more target proteins to be used to study them for small-molecule binding interactions.

The binding interactions resemble those of known small-molecule inhibitors as opposed to those of substrates and peptidic inhibitors.

Many nuclear import pathways are not valid drug targets, due to lack of specificity in NLS-import factor interactions; however, the huntingtin NLS has a unique structured IVS that could be exploited as a binding region for small molecules.