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The data suggest that 5-HTBP is a good structural model for examining ligand binding interactions, and functional experiments on the 5-HT3 receptors yield additional information on binding modes that cannot readily be ascertained from structural information.
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Ions removal efficiencies as a function of a DMC content, b AM + AMPS content, c AM content, d AMPS content and e the proposed binding interaction between functional groups and pollutants.
The network was built via the shortest path of maximum 2 steps, and using only curated interactions and functional and binding interactions.
This was dependent on HSJ1a client binding ability, ubiquitin interaction and functional co-operation with HSP70.
To vividly explain the reason for the desalination performance, the binding interaction between the functional groups on the polymeric shell with ions and organic emulsion droplets is further illustrated in Fig. 4e.
Each edge in the network indicates either a binding interaction or a functional linkage or both between a pair of proteins.
The relationship between target sequence variation in HSP72 binding affinity and functional interactions with HSP72 was addressed in our published work using a reverse genetics system to measure HSP72-dependent changes in MV transcription and genomic replication (15).
In each case, we used: shortest paths algorithm; merged network; not including canonical pathways; 1 maximum step in the path; showing disconnected seed nodes; showing shortest path edges only; using low trust, functional, and binding interactions for network building, and not using compound-target interactions.
This region contains highly conserved domains that are responsible for GTP binding and hydrolysis and functional interactions with regulators and downstream effectors.
The resources provided by bZIPDB include (1) protein interaction data including direct binding, phosphorylation and functional associations between bZIP TFs and other cellular proteins, along with other types of interactions, (2) bZIP TF-target gene relationships, (3) the cellular network of bZIP TFs in particular cell lines, and (4) gene information and ontology.
Networks were built using functional and binding interactions unless transcriptional regulation is specified.
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