Sentence examples for binding interaction is important from inspiring English sources
Additional experiments provided genetic evidence that this binding interaction is important for telomerase to lengthen telomeres appropriately.
The RGD motif in human IGFBP-2 has been reported to be involved in binding to integrin and this interaction is important for IGFBP-2-induced SNB19 glioma cell migration [23].
But if the proposed cation-π interaction is important for AdA binding, mutation of R504 might additionally reduce AdA binding by disrupting interactions with its adenine ring.
It is possible that unlike eh1 and WRPW motifs, an extended interaction is important for stable binding.
Direct interaction is important to Matt Leacock, too.
What is more, these data support the notion that miR-200c interacted with the TUBB3 3′UTR in hypoglycemia and that such an interaction was important for HuR binding and increased expression of TUBB3 under stressing conditions.
Incorporating other forms of interaction are important.
The proximal ubiquitin does not seem to contribute significantly to substrate binding, although its interactions are important during the transition state of the reaction, as revealed by site-directed mutagenesis experiments with AMSH, which showed that mutation of residues that bind to the proximal ubiquitin affects kcat but not KM.
DOI: http://dx.doi.org/10.7554/eLife.03604.023 From our structural and binding studies, we learned that ribose interactions are important for CNT binding but nucleobase interactions are less stringent and can even be modified to improve binding.
Increasing the length of the alkyl chains in a tetraalkylammonium ion increases its binding affinity, consistent with hydrophobic interactions being important in binding.It has been suggested, on the basis of mutagenesis studies, that fatty acids can also bind to this central hydrophobic cavity and binding of tetraalkylammonium ions and fatty acids is competitive.
This suggests that interactions between aromatic rings (π-π interactions) are important in binding to inactivated state.
