Sentence examples for binding interaction did not from inspiring English sources

This binding interaction did not appear to be compromised in any of the Vps1 mutants.

Combined, these results indicated that a region located between the Uls1 SIMs and ATPase domain was required and sufficient to interact with Slx5 in vivo and that the Uls1-Slx5 interaction did not require binding of Uls1 or Slx5 to SUMO.

In the case that an interaction did not have at least one DNA binding domain, this interaction was not considered.

Using an in vitro TR-FRET assay we demonstrate that this interaction does not change the binding of PGC1α co-activator peptide to recombinant PPARα ligand binding domain.

In further experiments, we show that BRD4 associates with acetylated p53 but that this association is not inhibited by JQ1 indicating that the protein protein interaction does not involve bromodomain binding of acetylated lysines.

Mutational studies have also shown that the direct Tat:7SK RNA interaction does not require Tat's pTEFb-binding capacity, but is solely dependent on Tat's RNA-binding activity, which is attributed to its RNA binding-domain (RBD, G48-R57 14. G48-R57 14

Comparisons across all predicted interactions did not reveal a clear correlation between predicted binding energy and target regulation.

Indeed, more than half of the interactions did not involve the previously defined PDZ-domain binding C-terminal motifs.

All these results: the lack of clear orientation bias, tolerance to distance change and the lack of periodicity together seem to indicate that binding site interactions do not follow strict rules, at least in these tested cases.

The comparison between PI(3 P (strong binding) and PI 5 P (weak binding) indicates that electrostatic interactions do not predominate, as suggested previously [ 25, 32].

This suggests that the nuclease domain-DNA interactions do not provide sufficient binding energy or their half-life is too short relative to the catalytic step of cleavage.