Remarkably, we found a strong association between the JIL-1 binding intensity and the maintenance of clusters including OBP genes (Spearman's rank correlation coefficient: ρ = 0.617, P = 0.010; fig. 4 D).
Here and forth, designations of the binding intensity and the corresponding promoter are the same, and two numbers are given for PEP-promoters, with the first number being the binding intensity under knockout and the second number being the intensity in the wild type.
Considering one probe in a certain SNP probeset, we have the basic model [ 39, 40]: (1) I = I s + I bg + ε, where I, I s and I bg stand respectively for probe intensity, specific hybridization intensity caused by target sequences and background nonspecific binding intensity, and ϵ is the measurement error.
In human with MELAS syndrome, the model predicts a 1.21-fold decrease of the mTERF·DNA binding intensity and a 7.75-fold decrease of the HSP1 promoter efficiency.
ChIP-seq read count represents ERα binding intensity, and ChIP-seq binding sites represent the number of binding sites.
We further examined whether the high JIL-1 binding intensity and TE chromatin state represent particular features of clusters including OBP genes.
By tissue microarray, Ec-LDP-TIMP2 showed high binding intensity and selectivity to human NSCLC specimens as compared with the matched non-cancerous tissues.
In mammals, there appears to be minimal correlation, if any, between TF binding intensity and their presence at orthologous regions in divergent vertebrate species; however, in flies, TF binding intensity and TF binding conservation appear to correspond closely.
Lectin toxicity corresponded to membrane binding intensity, and was profound in case of WGA (ID50 at 2.5 5 μg ml−1).
Of note, tetramer binding intensity and antigen sensitivity did not correlate for some hybrid TCRs, such as A1-T/B11 A1-S/B11/B11 (Fig. 2d).
The lectin-sperm binding intensity (F532) and the local background intensity (B532) were extracted by GenePix pro 6.0 (Molecular Devices, Sunnyvale, CA).
