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The PDB was used so that structural binding information would be available for comparison to potential biofragment-bound crystal structures.
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We also show that the ligand binding sites (local information) overweight the sequence similarities (global information) in ligand-target binding, and introducing too much global information would be harmful to the predictive ability.
Any information would be appreciated.
Your sensitive genetic information would be safe.
"…Written information would be helpful.
The information would be validated and updated.
Such information would be very useful.
A more stringent binder would have a higher information content, since the variability in its binding targets would be smaller.
Thus, it should be possible to analyze the sequence information of all possible isoforms to obtain their homophilic binding affinities relative to heterophilic binding, which would be a time and resource-consuming task if performed using experimental approaches.
If binding is independent then no information exchange would be observed.
Although these targets would not be internationally binding, they would be subject to outside verification.
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