Sentence examples for binding information of proteins from inspiring English sources
A model is presented that aims to provide a rigorous theoretical framework from which binding information of proteins from FRAP data can be extracted.
The PDB is a repository of detailed three-dimensional (3D) structural information of proteins and other molecules, including information on the binding between ligands and proteins.
Finally, Hopkins and co-workers used their method to predict the drug-likeness of 167,045 ligand compounds that bind to 1,729 proteins (on the basis of binding information from ChEMBL, a database of biologically active compounds11).
This is the first modeling study for TRESK that can provide structural information of the protein including ligand binding information.
The information of drug-protein binding can be obtained without separation.
Therefore, we proposed that EIPP, which provides the evolutionary information and physicochemical properties information of the protein, could effectively distinguish RNA-binding proteins from nonbinding ones.
As a source of information about binding partners of yeast proteins we combined the data from two independent high-throughput two-hybrid experiments: the core dataset of Ito et al. [ 4] (806 interactions among 797 proteins) and the extended Uetz et al. dataset [ 3], downloaded from the website of this group (1446 interactions among 1340 proteins).
Although the above-proposed SGTP affinity profiling assay is effective in identifying specific SGTP-binding proteins, it provides little information about the binding selectivities of these proteins toward SGTP versus other endogenous nucleotides (i.e., ATP and GTP).
It is highly sensitive and may be used to obtain qualitative as well as quantitative information in determination of protein binding parameters of various DNA molecules [ 4- 6].
All 3D structures of natural products and information of binding site of target proteins can be accessed on the website.
This result suggests that the crystallographic structure of a protein-DNA complex indeed contains enough information to locate the binding sequences of a protein.
