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Binding of quinlukast to rat plasma proteins was very high (approx. 99.7%) and this binding influenced distribution volumes of quinlukast.
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146 Another hypothesis is based on the observation that alpha-synuclein binds to lipids in the plasma membrane 147 and this binding influences the fibrillization capacity of alpha-synuclein.
This might indicate that the relationship between SERT and DAT binding influences the motor phenotype of CD, more specifically whether a patient develops jerks or not.
To test whether nucleotide binding influences the mislocalisation of Irgm1 caused by EGFP tagging, the Irgm1 nucleotide binding deficient mutant (S90N) was tagged with EGFP at N or C terminus and expressed in MEFs.
We then tested whether erythrocyte binding influences Ad5 circulation kinetics.
Ca2+ binding influences the ability of CaM to interact with target proteins.
The oriented immobilization via amide covalent binding influences the conformational stability and the activity of immobilized antibodies.
We propose that Cas8/Cas8′ is part of Cascade, contributing to PAM and structure specific nucleic acid binding, influencing interaction of Cas5 Cas7 with nucleic acids.
Our studies directly compare these two types of Aβ inhibitors and address whether the location of inhibitor binding influences the structure or formation of the different size oligomers.
Our studies show that the location of inhibitor binding influences their ability to block the formation of the high MW oligomers.
The question of whether ATP binding is sufficient to trigger the high-affinity to low-affinity switch can be explored by analysing how ATP binding influences lipid A-binding affinity.
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