Sentence examples for binding induces substantial changes from inspiring English sources

In general, ligand binding induces substantial changes in the active site electrostatic microenvironments for all four positions where the SCN probe was incorporated.

Here, we show by intramolecular Förster resonance energy transfer spectroscopy that ligand binding induces substantial conformational changes in the ectodomain of ifnar1 (ifnar1-EC).

It is, however, possible that a further decrease in pH, particularly in the range near the pKa of carboxylates (4 4.5) may induce substantial changes in the RKIP pocket structure and its ligand-binding properties.

In Sweden, the goal to replace fossil fuels could induce substantial changes in the current management and use of forests.

We found that focal electrical stimulation of cortical neurons induced substantial changes in the response magnitude, response latency and receptive field of ipsilateral cochlear nucleus neurons.

Basal LXRα overexpression induced substantial changes in genes relating to metabolism (Fig 4A).

Feeding insects can induce substantial changes of the host plant transcriptome.

ZA treatment did not induce substantial changes in the morphological appearance of the cells (Fig. 1 ).

In a similar study the application of the fungicide enostroburin induced substantial changes in bacterial community in wheat phyllosphere [ 18].

One other report suggested overuse induces substantial changes in gene expression in this animal model [ 8].

Thus, DCC binding induces no significant changes to the overall conformation of the cassette.