Sentence examples for binding induces significant changes from inspiring English sources
Instead, we find that Na+ binding induces significant changes in helix arrangements in the 6-helix bundle.
The binding of G3P induces significant changes in the chemical shifts for multiple nuclei in the regions of loops 6 and 7 of wild-type cTIM, and nuclei associated with residues 10 13, 94, and 95, but substantially smaller changes in the chemical shifts for the corresponding nuclei of the L6RM.
crRNA binding induces significant conformational changes that are likely to stabilize crRNA binding and facilitate target RNA recognition.
Consistent with the results of the kinetic study, the predicted ATP-binding site was distinct from that of dNTP and NRTIs [23], and single-amino-acid substitutions at positions 113 and 219 around the predicted ATP-binding site indeed induced significant changes in the Ki value of ATP.
Upon KIX-binding, pKID undergoes a transition from disordered to well folded.[7] This suggests that KIX-binding induces significant conformational change in bound pKID.
In addition, GTPγS binding dose-response curves of Epi-pretreated cells revealed a significant increase (1.8-fold, p = 0.012) in the EC50 of Epi to stimulate GTPγS binding through the WT α2B-AR, whereas Epi pretreatment did not induce significant changes on the EC50 for the Del α2B-AR α2B-AR
This observation suggests that the substrate modifications do not induce significant changes of the Fe(III)–S Cys) bond strength relative to NHA binding and do not sterically perturb the heme conformation and its environment.
