Sentence examples for binding in vitro and from inspiring English sources
Results: The dual-labeled probe 64Cu-RGD-C DOTA -ZW-1 showed integrin specific binding in vitro and in vivo.
We identify a second DNA contact and a metal center within the FANCM pseudo-nuclease domain and demonstrate that mutations in either region impair double-stranded DNA binding in vitro and FANCM-FAAP24 function in vivo.
The viral protein 1 (VP1) coat protein of the O1 British field strain serotype of foot-and-mouth disease virus is a high-affinity ligand for αvβ6, and we recently reported that a peptide derived from VP1 exhibited αvβ6-specific binding in vitro and in vivo.
In most cases, antifungal activity was correlated with cyclophilin A binding in vitro and inhibition of the mixed-lymphocyte reaction and interleukin 2 production in cell culture.
Standard COX-2 inhibitors were used to test for specificity of [18F]Pyricoxib for COX-2 binding in vitro and in vivo.
Our ITC data demonstrate that Asp mutants cannot mimic phosphoserine for B56 binding in vitro, and consistent with a previous study (Kruse et al., 2013), illustrate that Ser670/676 phosphorylation can indeed promote the direct interaction between B56 and BubR1, while Thr680 phosphorylation may not be significant.
Importantly, the DNA-binding regions appear to co-operate during telomeric ssDNA-binding in vitro and establish a dynamic 'DNA-binding equilibrium' in which the primer can interact with any or all of the DNA-binding domains [28], [29].
However, the interaction is crucial, as CTCF binding enhances UBF binding both in vitro and in vivo.
In summary, mutation of Adr1 serine 98 to the phosphomimetic amino acid aspartate reduced DNA binding affinity in vitro and led to loss of in vivo binding detection.
Mechanisms of binding and the relative binding affinity of various BPs to bone mineral are introduced, including common methods for measuring binding affinity in vitro and in vivo.
