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The target for Na+ binding in this study has been Ser-124.
4´OH-PCB 12 had the highest-affinity binding in this study, and it exhibited a significantly lower dissociation constant (Kd1 = 2.7 nM) than its sulfate (16.8 nM) and T4 (4.7 nM).
Consequently, to offset the effect of biases in primer binding, in this study we used three newly developed primer sets for targeting benthic macroinvertebrate taxa commonly used in biomonitoring.
The absence of overall group differences in F-fallypride binding in this study may seem to be at variance with previous reports of reduced C-raclopride binding in selected brain regions of the left hemisphere in adult patients with ADHD compared with control subjects (Volkow et al., 2007 b, 2009).
Because claudin-3 and -4 are the epithelial receptors for Clostridium perfringens enterotoxin (CPE), and are sufficient to mediate CPE binding, in this study we evaluated the in vitro and in vivo bioactivity of the carboxy-terminal fragment of CPE (i.e., CPE290-319 binding peptide) as a carrier for tumor imaging agents and intracellular delivery of therapeutic drugs.
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Only Fmo1 displayed an absence of AHRE motifs in the region examined, while only Tiparp demonstrated AHR-binding in this study.
The promoter region of MSMEG3224, a region not identified as a GlnR binding site in this study and included as a negative control, showed no GlnR binding.
It can also be seen from Fig. 11 and Table 7, there is a good linear correlation between experimental inhibition efficiencies and calculated binding energies in this study.
As a proof-of-principle, we assessed AR chromatin binding profiles in this study.
Therefore, we focus on the protein-ligand binding site in this study.
This study used wild-type worms expressing exogenous DAF-16::GFP, but the number of binding events in this study was exceptionally high.
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