Sentence examples for binding in this region from inspiring English sources
Binding is dependent on the DNA-binding domain, as FruMBmut showed no significant binding in this region.
However, the pons might be considered a pseudo-reference region [35], provided the experimental conditions and physiological state of the animals does not affect tracer delivery and binding in this region across the different groups.
To further resolve binding in this region, we looked for direct GR binding sites by searching for a consensus GR binding sequence.
In the literature, associations of the 16189 variant in the CR of mtDNA with diseases have been hypothesized to result from altered protein binding in this region, subsequently leading to changed mtDNA replication [3].
50, 51 On the other hand, I-salmon calcitonin, which labels both calcitonin and amylin-binding sites, 52 shows binding in this region of rat and monkey brain.
While this region was not required for differential expression, it is likely that additional factor binding in this region increases expression.
Both CysO and MoaD form a key binding interaction with their respective binding partner in this region.
Comparative Genomix analysis, on the other hand, showed no conserved putative ets binding sites in this region, whereas other transcription factor binding sites, such as RFX1, were found to be conserved.
Site-directed mutagenesis and computational docking studies are consistent with the second site being directly involved in binding; mutations in this region significantly reduced the CP binding affinity (up to 12-fold reduction in Kd), while changes in site 1 had only minimal (≤2-fold) effects.
TFSEARCH and TESS programs were used to search for putative transcription factor binding sites in this region, which reports two putative NF-κB binding sites to be respectively situated in the region -315 to -306 nt and -271 to -262 nt.
We identified substantial Dichaete binding across the AS-C and almost all of the core binding intervals in this region overlap with known RedFly enhancers (ac_pg7 and ase_F2.0) or regulatory elements identified by the FlyLight project [ 45, 46].
