Sentence examples for binding in the white from inspiring English sources

AV-45 has been reported as showing non-specific binding in the white matter.

In the ARG experiments, [11 C]N-methyl-SSR504734 showed specific binding in the white matter and pons.

[H]AZD2184 demonstrated the highest signal in cortical tissue, but nonspecific binding in the white matter was lowest for [H]AZD2995.

Although tau imaging in AD would favor low white matter binding, specific binding in the white matter would probably benefit the differential diagnosis of CBD and PSP [ 73] or identify cases of white matter tauopathy with globular glial inclusions [ 4, 5].

Due to AV-45 non-specific binding reported in the white matter [11], regional mean standardized uptake values (SUVs) were calculated from the cortex only as follows: For each subject, CT scan obtained during AV-45-PET acquisition was first linearly registered onto the MRI anatomical T1 image using FSL software.

Since our previous autoradiographic study demonstrated that there was minimum specific binding of [11C]HMS011 in the white matter of the monkey brains [15], we used the centrum semiovale as reference tissue in the current study.

When comparison between these two binding sites identified in the white fragment and the LTR fragment bound by ZAM-IN have been made, some homology was clearly detected between the second binding site of w3 and a motif located between nucleotides 30 and 45 of the LTR (Fig. 4C).

In comparison with high specific-to-nonspecific tau binding in the gray matter, the white matter may have an equal ratio or a higher nonspecific-to-specific binding ratio given the reduced blood flow compared with gray matter.

Hence, the low amount of unspecific retention of [18F]FIBT represents a substantial improvement, because compared to [11C]PiB, most 18F-labeled AD tracers in advanced clinical trials show a higher tendency towards unspecific binding to the white matter in humans [52,55].

In control subjects, [C]AZD2995 binding was equal in the grey matter, white matter and cerebellum, while [C]AZD2184 binding was somewhat higher in the whiter matter.

Specific [125I]IMPY or [3H]SB-13 binding can be clearly measured in the cortical gray matter, but not in the white matter of AD cases.