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Exact(6)
In particular, we observed significant enrichment of DGCR8 binding in the region within 200 nt downstream of the TSS (sense versus antisense ks test p < 2.2e-16; Figure 2B).
A high degree of specific binding, in the region of 85% of the total binding, was observed when ETA+ETB receptors were observed together and when ETA receptor binding was performed (in the presence of the ETB antagonist BQ788).
The addition of excess zinc abolished ECAO activity, and it is possible this is due to binding in the region of the active site base, forcing TPQ into a nonproductive conformation (54, 55).
In order distinguish between clustering/aggregation and direct binding in the region of the PV we used spatial stereology, which maps the quantities of organelles in the cytoplasm with minimal bias (McCullough and Lucocq, 2005).
To determine whether p53 was directly bound to the promoters of miR-16-2 and miR-26a-1 genes, we performed ChIP assay using p53-specific antibody.To independently validate the results of luciferase assay, we analysed p53 binding in the region from −2000 to +3000 of the miR-26a-1 gene using a series of primers.
For type IV response genes, in the absence of exogenous ligand occupancy of PPARβ/δ was near the TSS with a cluster of binding in the region upstream of the TSS and some skewness in the region downstream of the TSS.
Similar(54)
As shown in Table 2, there were large differences among the three patients with respect to H-THK5117 binding in the regions studied.
For each potential binding site in the region, we selected 20 virtual RNA fragments that encompass the assumed binding site.
Importantly, much lower binding of p53 was observed at the amplicons −500 and +3000, indicating that the maximal p53 binding occurs in the region from −2000 to −1500.
For Iowa-06 and the other selected strains the very marked region of predicted DR high affinity binding in the 275 279 region is absent.
Ecdysone-induced protein 74EF (Eip74EF), has putative binding sites in the region >5 kb from the start site.
More suggestions(15)
binding in the absence
binding in the sense
binding in the diencephalon
binding in the brain
binding in the cortex
binding in the syn
binding in the colon
binding in the striatum
binding in the stroma
binding in the caudate
binding in the myocardium
binding in the antigen
binding in the hippocampus
binding in the reference
binding in the way
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