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This metabolite may have a higher receptor binding affinity than authentic 2b, and thus be responsible for the apparent receptor-mediated binding in the mouse brain.
This study demonstrates that high-resolution SPECT/CT is capable of accurate, repeatable, and semiquantitative measurement of 123I-β-CIT DAT binding in the mouse brain.
Although we cannot identify the cause of the species difference between mice and monkeys, some structural characteristics might be responsible for the high nonspecific binding in the mouse brain.
Alteration of the corresponding amino acid also inhibits α-amanitin binding in the mouse protein (Bartolomei and Corden 1995).
The level of covalent binding in the mouse hepatocytes exceeded those of the rat and guinea pig at high doses of PhIP.
A study published in 2002 demonstrated the feasibility of pinhole SPECT for measuring striatal DA D2/3 receptor binding in the mouse brain in vivo [ 107].
Similar(51)
To determine whether p53 can bind to either of the two putative binding sites in the mouse Tigar promoter, chromatin-immunoprecipitation was carried out in mouse 3T3 cells treated with CDDP to activate p53.
Although there were no obvious potential ATF6 binding sites in the human or rat VEGFA promoters, there was one potential ATF6 binding site in the mouse VEGFA gene at +1.4 kb relative to the transcription start site.
More than 90% of the residues identified at the QZ59-SSS inhibitor binding sites in the mouse model were observed within 3.5 Å of the preferred SSS analogue binding cluster in the human Pgp, and 100% were found to be identical for the RRR analogue docking.
We have previously identified an interferon regulatory factor (IRF) binding motif in the mouse AT2 receptor gene promoter region.
Using a carefully constructed test set of verified binding sites in the mouse genome, the authors report that their method can reduce false positive rates, and that DNA duplex stability and nucleosome occupation data can improve the accuracy of transcription factor target gene predictions.
More suggestions(17)
binding in the absence
binding in the sense
binding in the brain
binding in the diencephalon
binding in the cortex
binding in the syn
binding in the colon
binding in the striatum
binding in the caudate
binding in the antigen
binding in the myocardium
binding in the stroma
binding in the hippocampus
binding in the way
binding in the reference
binding in the sodium
binding in the case
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