Sentence examples for binding in the monkey from inspiring English sources

[11C]TASP0410457 binding in the monkey cerebellum and brainstem was noticeably decreased in the presence of 10 μM of unlabelled TASP0410457 or ciproxifan (Fig. 7f, g).

For new radioligands such as [11C]DAA1106, specific binding constitutes 80%to90%0% of the total binding in the monkey brain [36].

Next, we examined the effects of subchronic administration of the NMDA receptor antagonist phencyclidine (PCP: 0.3 mg/kg, i.m., twice a day for 13 days) on the distribution of [11C]CHIBA-1001 binding in the monkey brain.

However, kinetic analysis of the results of a PET study of [11C]doxepin showed 30% specific binding in the monkey brain, and a larger specific binding rate (36%) in the human brain [33].

The high LipE scores for [C] 7– 9 are consistent with the high proportions of TSPO-specific binding found in the monkey brain imaging (Table 3).

In the preliminary semi-quantitative analysis, the ratios of K in each ROI (K (ROI)) to K in the cerebellum (K (CE)) were calculated to determine the binding of α7 nAChRs in the monkey brain.

Third, we found a reduction of [11C]CHIBA-1001 binding in the frontal cortex of the monkey brain after subchronic administration of PCP.

This finding was also consistent with the presence of specific binding components for H3R ligands in the monkey cerebellum demonstrated previously [30, 31].

Our present data demonstrated the presence of displaceable binding sites for [11C]TASP0410457 and [11C]TASP0434988 in the monkey cerebellum and brainstem including the pons, similar to the previous reports on [11C]GSK189254 [14, 14, 29].

These results demonstrate that Ap-1 transcription factor (5′-TGTCTCAT-3′) has a specific binding site for the monkey 20α-HSD gene located in the -281 → -274 region.

Given that A2AR distribution is heterogeneous, with only a very small amount of extrastriatal-specific binding, either the frontal cortex in the rat [3], the cerebellum in the monkey [10],[11], or centrum semiovale [7] or cerebral cortex [8],[9] in human, was used as a reference region to estimate non-displaceable binding of 11C-TMSX.