Sentence examples for binding in the minor from inspiring English sources

These are (1) binding in the major groove, (2) binding in the minor groove, and (3) intercalation between nucleotide bases.

Hairpin lexitropsins fold onto themselves; as a result, their binding in the minor groove resembles that of dimeric molecules.

Strong positive induced CD signals upon titration of the compound to DNA sequences are characteristic of binding in the minor groove of DNA.

The dendrimer provides the positive charges for non-specific binding and the cyclopeptide with a sequence related to the IHF α-arm specifically binding in the minor groove.

Binuclear RuII compounds such as Λ,Λ-B differ from both small molecules such as netropsin and many others, 28 as well as proteins 29 binding in the minor groove.

A ligand-observed NMR screen of a thermal-shift-enriched fragment library identified several importin-α binding fragments that appeared to bind in the minor site.

We found that an increase of TF binding affinity in the minor allele was not necessarily associated with a gain of regulatory potential in the cancer cell line, and vice versa.

Their HMG-box domain fulfills the function of DNA-binding, with the peculiarity that it binds DNA in the minor grove (reviewed in [18]).

A series of head to head linked dimers of heterocyclic amino acids has been prepared for investigation of affinity and selectivity in binding to the minor groove of DNA.

The X-ray crystallographic structure of the complex between spectinomycin and the 30S subunit of Thermus thermophilus confirms that the antibiotic-binding site is in the minor groove near the end of helix 34 of 16S rRNA.

The Lamarckian genetic algorithm (AutoDock 3.0) was used to model the interaction/binding between m-iodo-p-methoxyHoechst (IMH), a ligand available in the Protein Data Bank whose binding to the minor groove of DNA has been demonstrated (crystal structure), and the oligonucleotide d CGCGAATTCGCG 2.