Further, our data showed that p85α can bind PTEN, promote PTEN activity and membrane binding in the absence of other proteins.
Alternatively, non-immunized rodents were treated with folate-FITC, which binds readily to FR+ cells but cannot mediate anti-FITC antibody binding in the absence of KLH-FITC immunization.
This suggest, that c-Rel binds to Foxp3 via its C-terminal transactivation domain and the loss of binding in the absence of the entire RHD and IPT indicates that dimerization of c-Rel is required.
In vitro, the modified probe retains high target binding in the absence and presence of albumin.
In addition, the host bacteria did not show any binding in the absence of the TSPs on the surface.
Batch equilibrium experiments were also performed for both PHA and PFA to investigate Pb-DOM binding in the absence of soil.
The ternary complex model, designed to describe agonist binding in the absence of GTP, is often extended to G protein activation.
While no binding to the negative control region (HBB) was observed in immortalized human fibroblasts with or without Δ133p53 overexpression, the miR-34a, p21WAF1, BAX and PUMA promoter regions showed significant binding in the absence of overexpressed Δ133p53 (Figure 6c, Vec).
Moreover, the combined analysis of antibody titers against recombinant gp41-MinTT and the original gp41-Min proteins showed that mice immunized with recombinant gp41-MinTT presented gp41-MinTT binding in the absence of gp41-Min titers, indicating that the response was exclusively focused against the immunogenic TT epitope (Fig. 3b).
Membrane association of the myristoylated alanine-rich C kinase substrate (MARCKS) protein appears to involve myristate-dependent binding in the absence of a myristoyl protein receptor.
Would developing countries accept a US pledge as binding in the absence of Senate legislation - given that on the Kyoto Protocol, the US first signed, then declined to ratify, then withdrew?
