Unfolded CH1 does not bind the luminal domains themselves, leading to the conclusion that the conformational change in BiP engendered by peptide binding must in some way alter access to the site(s) of luminal-domain binding.
However, our data suggest that further mutation of the C-domain ECM-binding domain in some way rendered the mutant more susceptible to MMP-1 proteolysis.
All students, in both conditions, who included reversibility described that subunits might dissociate after binding, given that the binding is incorrect in some way, as exemplified by the following posttest response from a student in the image condition: When a virus is formed, small pieces are put together to form a larger complex.
There are three main classes of bacterial hemoglobins, with a number of functions, although each of these involves oxygen binding or sensing in some way (Vinogradov et al. 2006; Vinogradov and Moens 2008).
We suggest that the composition, location, and distance between actin binding periods in the tropomyosin molecule contribute to the components of binding in different ways.
Overlapping of TFBS with CpG "traffic lights" may affect TF binding in various ways depending on the functions of TFs in the regulation of transcription.
The new policy went into effect last month, but it was also a part of the settlement of the lawsuit in federal court, making it binding in a way that some of the other ordinances around the country are not.
"My concern is that the Bush administration, in a weakened state politically, ends up trying to rush an agreement that in some ways might be binding to the next administration," Mr. Obama said, "whether it's my administration or Senator McCain's administration".
The remaining missense mutations in the DBD may be protein destabilizing, but may also prevent DNA binding in another way, or have some as-yet-unknown effect on IRF6 function.
And we're exploring with Russia and we're discussing within the administration the best way to make this a legally binding or codified agreement in some way".
