Sentence examples for binding in response to from inspiring English sources

As TRAF6 binding in response to CD40 ligation is, at least in part, responsible for CD40-mediated NF κB activation, we propose that FAF1 regulates NF κB in the context of CD40 signalling through competition with TRAF6 for its CD40-binding domain.

It has been reported that PML-RARA forms multimerization via disulfide-mediated covalent binding in response to AS2O3, and subsequently triggers the NB formation (Jeanne et al., 2010).

How is it that dTCF binding in response to WG signaling inhibits expression of dpp but activates other genes?

Compared with wild type platelets, PP1cγ−/− platelets showed only marginally decreased soluble fibrinogen binding in response to PAR-4AP (P = 0.05) (Figure 2C).

We found no significant increase in Swr1 binding in response to a DSB, which might be due to differences in growth conditions (minimal versus rich medium).

A ∼42% (p = 0.02) and ∼45% (p = 0.01) decreased fibrinogen binding in response to 0.01 U/ml and 0.02 U/ml of thrombin was observed in PP1cγ−/− platelets (Figure 2B).

Downstream of JNK, we observed increased phosphorylation of c-Jun, enhanced activating protein-1 (AP-1) luciferase reporter, and AP-1/DNA-binding in response to gal-1.

For relatively strong STAT1 binding sites, the binding preferences in response to IFN-γ versus IFN-α showed substantial correlation.

Given their positions flanking the amino acids responsible for eIF4E binding (amino acid residues 53 59), it is conceivable that Thr46 and Ser65 are responsible for the phosphorylation-mediated modulation of eIF4E binding occurring in response to mTOR activity.

This allows transcription activation of cognate promoters to be enabled through the highly conserved DNA-binding domain in response to effector binding [21], [25].

We use ChIP-Seq to identify members of the Pho7 regulon and characterize Pho7 binding dynamics in response to phosphate-limitation and Csk1 activity.