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The association of Dp71 + Dp40 signal transduction plus transmembrane receptor binding in relation to growth factors implies that the structural alterations thus far observed in the brains of patients missing Dp427 and Dp14027 may be further aggravated in patients missing Dp71 and Dp40.
Patterns of binding in relation to gene features were generally conserved across different cell types.
In the present study, we demonstrated not only SFN-induced down-regulation of telomerase in breast cancer cells but also explored possible epigenetic mechanisms such as demethylation at the first exon of hTERT and CTCF binding in relation to hTERT repression.
While the classic dissociation between working memory and long-term memory is currently under debate [49], future studies on working-memory binding in relation to episodic-memory formation may shed further light on the underlying neurocognitive mechanisms of the MTL memory circuit.
Consistent with this, substitution of Phe54 at the tip of the HCDR2 loop of CR6261 with leucine or alanine reduced binding in relation to hydrophobicity, and additive decreases in binding were observed when CR6261 mutants and HA mutants were combined (Fig. 9b).
To gain insight into the mechanism by which Paupar regulates gene expression, we examined its binding in relation to known functional regulatory regions.
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In the light of extensive regulation of non-coding RNAs by hypoxia, we reanalysed the distribution of HIF-binding in relation to the location of all transcripts.
Based on crystallographic data from 33 fragment-enzyme complexes, the fragments could be classified into R1 or R2 binders by their overall binding conformation in relation to the binding of the R1 and R2 side groups of imipenem.
Based on the determined crystal structure of the apo-protein we discuss heme binding properties in relation to structurally related proteins from other bacteria including functional chlorite dismutases.
Finally, in December, the UNFCCC began to pursue a legally binding treaty in relation to GHG emissions.
To investigate the timing and coordination of gene activation events, we tracked the recruitment of GCN5 (histone acetyltransferase), RNA polymerase II, Brd2 and Brd4 (acetyl-lysine binding proteins), in relation to a VP16-transcriptional activator, to a transcription site that can be visualized in single living cells.
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