Sentence examples for binding in introns of from inspiring English sources

As is shown in Fig.  1b, two regions from the phenoloxidase gene (with primers binding in introns of the gene) corresponding to the 5′ region (P1) and 3′ region (P2) were selected for PCR amplification.

In order to take the low level of intronic RNA into account, and anticipating that pre-mRNA may be present at levels approximately 1000x lower than mRNA (7), we have lowered the threshold for determining robust RBM47 binding in introns while maintaining a conservative cut-off of total HITS-CLIP reads in clusters in the vicinity of alternatively spliced exons (see Figure 4D).

Polymorphisms located in introns of genes can have significant effects on transcription that may be related to changes in the structure of binding sites of promoters or facilitators structure segments ("enhancers") or blocking ("silencers") within introns.

We noted a cluster of four putative E4BP4 binding sites in intron 4 of human APP.

The g.66493737C>T SNP is located within the sequence of a putative E2F transcription factor binding site in intron 1 of the MSTN gene.

As shown in Fig. 6 D and E, direct binding of Gfi1 could be documented to a Gfi1-binding site in intron 2 of IL7Rα, but not to putative Gfi1 binding sites present in intron 3, intron 4, or the promoter.

Recent AR ChIP-Seq reveals four peaks of AR binding among multiple introns of PSMA in LNCaP [ 28].

Focusing on a set of CTCF binding sites that were identified in an unbiased genome-wide analysis [ 41], we found CTCF binding sites in the introns of 20 imprinted genes (34.48%), which is a slight enrichment compared to 21.65% of the autosomal genes (χ2 test, p < 0.05).

More complicated types of regulation are implied by numerous examples of ribosome-binding sites in introns that are sequestered by RNA secondary structure [ 54- 58].

Overall these results strongly suggest that the chromatin segment surrounding the SOX9 binding site in intron 6 was depleted of nucleosomes.

Also revealing was that this enrichment was only seen for the HSF binding sites found in the introns of genes whereas the analysis of HSF binding sites in promoters and introns and in the genes that showed transcriptional changes showed enrichment in GO categories such as response to stress and transferase activity.