Sentence examples for binding implications from inspiring English sources

However, we also noticed significant differences in the geometry of the interactions between H524, E353, R394, and the hydroxyl moieties of E2 and the ligands with possible functional and/or binding implications.

The demonstration that glycoproteins can be important contributors to CTB binding has implications for the use of CTB to study the organization of lipids in the plasma membrane.

The involvement of chromatin in Hox binding has implications for the specificity of the downstream gene expression response to Hox regulation.

2. Aravind L, Anantharaman V, Koonin EV: Monophyly of class I aminoacyl tRNA synthetase, USPA, ETFP, photolyase, and PP-ATPase nucleotide-binding domains: implications for protein evolution in the RNA.

In view of the prominent role of protein flexibility in ligand binding and its implications for drug discovery, it is of great interest to identify receptor conformations that play a major role in biomolecular recognition before starting rational drug design efforts.

It is unclear whether these varying binding properties have implications for the ability of a specific antibody to modulate receptor function.

Thus, we conclude that the disordered WIPC fragment is comprised of regions with latent structure connected by flexible loops, an architecture with implications for binding affinity and function.

Subsequent biochemical experiments revealed that specificity of ligand recognition can be affected by point mutations outside of the binding pocket, which has implications for both the assignment and reengineering of riboswitches in this structural class.

Increased understanding of the degree to which the conformational space of a ligand is restricted upon binding may have important implications for docking studies, structure refinement and for function prediction methods based on geometrical comparisons of ligands or their binding sites.

This also has implications for binding and displacement of protein ligands other than RAP.

Below we shall assess the implications of binding competition by comparing Design I with Design III.