Sentence examples for binding helps from inspiring English sources

Cadherin binding induces oligomerization of the toxin by facilitating removal of the N-terminal region, while APN/ALP binding helps in oligomer membrane insertion.

Multivalent binding helps retain large particles that experience more powerful detaching forces than a ligand molecule.

In addition, departing from the standard PWM model (by adding dependencies between adjacent positions and non-linear contributions to binding) helps improve the models even further on both levels.

CTCF binding helps maintaining the maternal IC1 methylation-free, whereas on the paternal chromosome gamete-inherited DNA methylation inhibits CTCF interaction and enhancer-blocking activity resulting in IGF2 activation and H19 silencing.

Structures were solved of the enzyme crystallized in the presence of SAM (2.25 Å), and in the presence of SAM plus a 7-mer peptide (RVSG734YAV) analogue of the Gly734 region of PFL (2.8 Å), although ordered SAM binding is observed only in the latter structure, suggesting that substrate binding helps to order SAM in the active site.

This refractoriness of S-222611 to serum protein binding helps explain why S-222611 can exert advantageous activity over lapatinib in a cell-based test system which intrinsically contains serum protein and, thereby, can lead to potent antitumor activity in vivo.

"The landmark arbitration ruling in July, which is binding, helped clarify maritime rights in the region," Obama told a summit of Asian leaders in Laos on Thursday.

Both mechanisms have been advanced throughout the literature in a plethora of contexts, including the association of cNTnC·Ca2+ with Sp. In the induced fit model, Ca2+ binding to the cardiac system "sets the stage" for Sp binding, helping to overcome the "energetic barrier to opening".

For Rover, the function of the putatively co-opted transposases has not been assessed, but might involve protein domains that are useful for cells: Domains that mediate DNA binding, help regulate gene transcription, or aid in chromatin organization (Feschotte 2008; Sinzelle et al. 2009).

If gene expression were up-regulated by an activating TF, presumably one whose binding helped to recruit RNA polymerase (RNAP), then this could be achieved by tuning the activation potency of each bound TF protein, i.e., changing the probability per unit time that an RNAP will bind per bound TF.

Because Mediator interacts extensively with pol II, these results suggest that Mediator structural shifts induced by activator binding help stably orient pol II prior to transcription initiation.