Sentence examples for binding has the most from inspiring English sources

The mechanistic models are based on the assumption that the sum of the albumin and phospholipid binding has the most significant impact on reducing compounds' free concentration both in plasma and in tissues.

The CopB-B nucleotide-binding domain has the most primitive fold yet identified for this enzyme class.

However, antipsychotics such as clozapine, olanzapine, risperidone, sertindole and zotepine have different propensities for inducing metabolic effects, even though they have similar and only moderate binding affinity for 5-HT2C receptors; moreover ziprasidone, which has the most potent binding [ 58], is apparently largely free of metabolic side effects.

This class combines a modest subtype binding selectivity with inverse agonism and has the most favourable molecular properties for further lead optimisation towards a central nervous system (CNS) acting medicine.

Of the three mutations, Smc1 F584R has the most drastic binding defect.

Smc1 F584R has the most severe effect on binding.

The gene BMP4 (bone morphogenetic protein 4; ID: 652) had the most binding sites for the predicted TFs.

The POMs are bound differently: TEW-5 and -8 have the most binding partners and interact with four HEWL chains.

On the other hand, croconate is predicted to have the most binding affinity to a conformer with a more closed active site cleft, with less solvent exposure, as well as a smaller active site volume (vide infra).

Voxel-wise analysis of [C]PiB binding found the hippocampus to have the most widespread increases whereas immunohistochemistry showed this region had lower amyloid-β deposition than in the thalamus, cortex, and striatum.

In our results miR160 was also the family having the most ARF binding sites identified (10 out of 44 ARF binding sites were found in miR160 promoter regions).