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Although water molecules do play a major role in catalysis, their implication in binding has been studied in detail elsewhere (Barillari et al., 2007; Levy and Onuchic, 2006) and are not considered as ligands in the present work.
The association of C -1019 G C -1019 G 5-HT1Apromoterhism and 5-HT1A recepolymorphism handbeen studied in humans in three [C]WAY-100 635 PET studies [ 1, 12, 13].
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The effects of chaperone binding have been studied in detail for GBA (Lieberman et al, 2007).
The nanoscale organization and dynamics of IgE-FcεRI upon antigen binding have been studied with scanning electron microscopy (SEM), localization microscopy, and single-particle tracking (SPT).
B3 DNA binding specificity has been studied in three families: ABI3, RAV and ARF.
The role of the internal cavities on ligand binding pathways has been studied in mutants of HbI.
The DnaA binding site has been studied in very diverse bacteria such as Gram-negative Escherichia coli and Gram-positive Bacillus subtilis [ 49, 50].
The critical role of a cation π interaction between the cationic nitrogen of ligands and the conserved loop B aromatic side chain of the 5-HT3R-binding site has been studied extensively [ 15, 18].
Although DNA and RNA binding of sanguinarine has been studied extensively [12] [20], binding to proteins is yet to be investigated.
Recently, an alternative substrate C type lectin for the binding of HA has been studied, an alternate of sialic acid attachment (Upham et al., 2010).
Statistical inference of transcriptional regulatory networks from a combination of gene expression time series, promoter sequence and binding specificity data has been studied in [85] [87], [63].
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