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A significantly weakened intentional binding has been observed; therefore, it may be useful to highlight the necessity of prior awareness (see [19]).
Yet, flexibility in the modes of histamine binding has been observed, which appears to suit specific biological roles of the proteins.
The long chain fatty acid transporter FadL is predominantly active on fatty acids containing 16 or more carbons, and no binding has been observed for decanoic acid, therefore it is unlikely that changes in fadL expression would account for the differences we observed (Black 1990).
Subsequent molecular imaging studies using 11C-labelled PK11195 have been in line with postmortem findings, i.e. increased TSPO binding has been observed in patients with multiple sclerosis, Alzheimer's disease, Parkinson's disease, epilepsy, encephalitis and other central nervous system (CNS) disorders (see review [8]).
Strongest binding has been observed between the most hydrophobic macrolides, azithromycin and clarithromycin, to cholate and deoxycholate micelles, respectively.
Tight ligand binding has been observed in various hyperthermophilic enzymes, whose optimal working temperature is >80 °C.
Similar(48)
Although the ECD is not present in the crystal structure of mGluR1 dimer (4OR2) (Wu et al., 2014), conformational changes of the dimerized, isolated ECDs upon agonist binding have been observed in previously reported crystal structures (Kunishima et al., 2000).
In the case of overlapping TFBS, two mechanisms of cooperative binding have been observed.
No cross reactivity for the primary antibody's isotype or secondary antibody non-specific binding have been observed.
As expected for nucleases that process RNA substrates with a range of secondary structures, multiple modes of RNA binding have been observed across the Cas6 family.
Other examples of allosteric binding have been observed for JNKs, PAK1, CHK1, CK2, GSK3-β, PKC-δ, and p38, and a discussion of their binding modes can be found in a recent comprehensive review.
More suggestions(17)
binding has been investigated
binding has been shown
binding has been evaluated
binding has been determined
binding has been added
binding has been linked
binding has been reported
binding has been characterized
binding has been solved
binding has been estimated
binding has been quantified
binding has been predicted
binding has been found
binding has been noted
binding has been examined
binding has been implicated
binding has been considered
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