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Eph-ephrin binding has been linked to tumor biology and VEGF has been reported to participate in the tumor angiogenesis regulated by Eph-ephrin.
The type 1 IGF receptor binding has been linked to tumour development in rodents [ 22] and these findings have led to the discontinuation of specific insulin analogues.
ErbB1/erbB2 receptor tyrosine kinase signalling mediated by EGF binding has been linked to integrin expression via effects on the focal adhesion complex [ 21].
The activity of S1R itself depends on binding of endogenous and exogenous compounds, and ligand binding has been linked to receptor oligomerisation [18,20].
This binding has been linked to evasion from the host immune system and long-term persistence, as well as increased delivery of the CagA oncoprotein into gastric cells, all of which are linked to disease (Oleastro and Ménard 2013).
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ADAM12, reported additionally to cleave some matrix components as well as IGF binding proteins, has been linked to OA in genetic association studies (for example [ 17]).
We have shown here that the evolution of this and other key binding motifs has been linked to the divergence of methylation levels across a range of locations in the human genome.
A mutation in the methyl-cytosine DNA binding protein methyl CpG binding protein 2 (MeCP2) has been linked to RETT syndrome (Amir et al, 1999).
29 Tumor expression of the insulin-like growth factor-II mRNA binding protein, IMP3, has been linked to poor outcome perhaps due to its association with poor prognostic features including tumor necrosis and sarcomatoid differentiation.
Direct repression by p53 was confirmed using a luciferase reporter vector controlled by the human miR-17-92 miR-17-92 miR-17-92 a promotering site that has been linked to miR-17-92 repression (Yan et al, 2009).
However, it was recently shown that the transcription factor SREBP-1 (for sterol regulatory element binding protein-1), which has been linked to the regulation of cellular lipid levels, activates gene expression of Nlrp1a and/or Nlrp1c, likely by binding directly to promoter regions, but not of Nlrp1b[ 27].
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binding has been evaluated
binding has been determined
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binding has been reported
binding has been characterized
binding has been solved
binding has been estimated
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binding has been predicted
binding has been found
binding has been noted
binding has been examined
binding has been implicated
binding has been demonstrated
binding has been considered
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