Sentence examples for binding has been in from inspiring English sources

In particular, the prediction of non-specific brain tissue binding has been in focus, for which in silico, in vitro, or bio-mathematical methods have been applied [6]-[9].

A significant reduction in TSPO binding has been found in gray matter in a small sample of drug-naïve, first episode psychosis patients, suggesting a reduced number or an altered function of immune cells in brain at early stage schizophrenia.

The association of C -1019 G C -1019 G 5-HT1Apromoterhism and 5-HT1A recepolymorphism handbeen studied in humans in three [C]WAY-100 635 PET studies [ 1, 12, 13].

The behavioral significance of the decrease in D2 receptor binding has been investigated in studies of cocaine abuse in addition to imaging studies in non-human primates and non-addicted human volunteers.

Finally, decreased M2R binding has been reported in the cingulate cortex in bipolar depressives (Cannon et al. 2006a), using PET-neuroreceptor imaging (Fig.  4).

However, nonspecific white matter binding has been reported in healthy subjects as well as in patients with Alzheimer's disease.

Importantly, increase in Brn-1 DNA binding has been shown in Brn-2 knockout mice brain (19).

Similarly, no difference in striatal D2 receptor binding has been observed in patients with TD compared to antipsychotic drug-treated patients without TD [ 43].

In particular, OPN binds CD44 proteins that contain v6-encoded sequences, and OPN/CD44v6 binding has been implicated in carcinogenesis (Ponta et al, 2003).

Aberrant 5-HT receptor binding has been implicated in suicide and SA [ 12]. 5-HTR1B bisdecreasedecreased in the prefrontal cortex of suicide brains [ 31].

This mechanism of DNA binding has been implicated in the drug's ability to inhibit transcription by HIV reverse transcriptase from single-stranded DNA templates.