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Exact(7)
Although β-alanine binding has been identified throughout the hippocampus, limbic structures, and neocortex, unique β-alaninergic neurons with no GABAergic properties remain unidentified, and it is impossible to discriminate between β-alaninergic and GABAergic properties in the CNS.
The DNA sequence required for LANA binding has been identified as the LBS.
The full length protein was shown to bind erythrocytes in a culture supernatant based erythrocyte binding assay [31] and the domain (region II) responsible for mediating the binding has been identified and characterized [8].
Intriguingly, no functional activity for this binding has been identified to date.
This domain contains homology with the C-type lectin, but to date no distinct carbohydrate binding has been identified.
The C-terminal DNA binding domain in SusR has no significant similarity to DNA binding domains of other known TFs; however, a putative helix-turn-helix motif presumably involved in DNA binding has been identified near its carboxy terminus [ 12].
Similar(53)
Using rational design, several amino acids involved in substrate binding have been identified and site-directed mutations have revealed that residue H115 plays an important role in binding.
Moreover, from the contour maps, the key features vital to ligand binding have been identified, which are important for us to trace the important properties and gain insight into the potential mechanisms of intermolecular interactions between the ligand and receptor.
Recently, using a PCR-based SELEX (Systematic Evolution of Ligands by Exponential Enrichment) procedure two consensus sequences for HMGA2 binding have been identified.
In mammals, important amino acid motifs involved in receptor binding have been identified and mutation studies reveal the importance of the N-terminus [ 20].
10, 11 Recently, a secondary hydrophobic binding site proximal to the primary phosphopeptide binding site has been identified by two independent approaches.
More suggestions(17)
impediments has been identified
binding has been mapped
binding has been investigated
binding has been shown
binding has been evaluated
binding has been determined
binding has been proposed
binding has been added
binding has been elucidated
binding has been linked
binding has been reported
binding has been solved
binding has been estimated
binding has been quantified
binding has been described
binding has been suggested
binding has been predicted
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