Sentence examples for binding groove that could from inspiring English sources

Several polar residues are also present in the Spy0129 binding groove that could account for its altered specificity; Tyr124 and Ser219 in Spy0129 replace Ala118 and Ile182 in SaSrtA.

Both classes of HLAs have a long binding groove that can bind peptides degraded from antigens.

This suggests that there are probably other substitutions in the PRCP binding groove that restrict the carboxy-terminal peptide length.

These exons determine the amino acid residues of the peptide binding groove that is important for antigen presentation.

This indicates that the prolyl hydroxylases may have a conserved binding groove that is able to accommodate proline-rich peptides via hydrophobic interactions.

By homology modeling, we identified two hydrophobic residues in the substrate-binding groove that contribute to substrate specificity.

Notably, most β-catenins have a conserved protein-binding groove that is undisclosed in several protein-ligand complex structures.

In the present paper, we reveal that hOGA possesses a conserved substrate-binding groove that is required for the interaction with O-GlcNAc proteins.

Sequences that are derived from common ancestry in different species, that have known gene products and peptide-binding grooves that are highly similar, and that could therefore select the same peptide for T-cell activation, were considered to belong to the same lineage [ 32].

(E ) Solvent occluded surface showing the two possible peptide-binding grooves that flank the peptide β-strand element (red).

The solution structure of the PDZ45 tandem shows that PDZ4 contains a deformed binding groove, but that this deformed groove stabilizes the structure of PDZ5.