Sentence examples for binding groove that can from inspiring English sources

Both classes of HLAs have a long binding groove that can bind peptides degraded from antigens.

This suggests that there are probably other substitutions in the PRCP binding groove that restrict the carboxy-terminal peptide length.

These exons determine the amino acid residues of the peptide binding groove that is important for antigen presentation.

By homology modeling, we identified two hydrophobic residues in the substrate-binding groove that contribute to substrate specificity.

Notably, most β-catenins have a conserved protein-binding groove that is undisclosed in several protein-ligand complex structures.

(E ) Solvent occluded surface showing the two possible peptide-binding grooves that flank the peptide β-strand element (red).

Close examination of structures of VAR F1L complexes with Bid and Bak and VV F1L complexes with Bim and Bak did not reveal major differences in BH3 domain binding to the canonical binding groove (Supplementary Figure 4) that can explain the startlingly different ligand-binding behavior.

The solution structure of the PDZ45 tandem shows that PDZ4 contains a deformed binding groove, but that this deformed groove stabilizes the structure of PDZ5.

The cyclin C binding groove can be checked by small ligand molecules leading to inhibition.

In other words, the restricted binding groove can only accommodate an X-Pro sequence on the amino-terminal side of the hydrolytically sensitive peptide bond.

It takes time to find a groove that you can play in.