Sentence examples for binding groove provides a from inspiring English sources

The analysis of the active cleft shows that the helix at the substrate binding groove provides a platform for the stable binding to the longer substrate, explaining the substrate specificity of TreX.

Bcl-xL, Bcl-2 and Bax interact weakly with the tumor repressor and transcription factor p53. NMR studies have shown weak specific interaction between p53 and Bcl-xL with a Kd of 370 nM that is released on Puma binding Bcl-xL in the groove, providing a potential allosteric mechanism for p53 activation of apoptosis.

Using structures currently in the PDB), five disordered sequences associated within a single binding groove in 14-3-3 14-3-3 14-3-3amprovidemany-to-onexampleling interactiofs.

The results reveal in some cases an unexpected resilience of the phosphopeptide binding groove to mutation and provide a better basis to predict the functional consequences of these variants.

Place the gasket onto the cover or into a groove provided for it in the case.

In 14-3-3 14-3-3 14-3-3ding groove in a strucommon dimeric protein can bindinged by multiple, distinct sequences provided by many different bindingrooveners.

Expansins contain two domains that form a binding groove for a glycan backbone.

In consistent with the structural homology of C. fulvum Ecp6, a shallow groove was observed in the LysM domain III that provides a binding site for chitin oligomers.

The side-chains of the peptide anchor residues interact with the polymorphic complementary pockets in HLA peptide-binding grooves and provide the molecular basis for allele-specific recognition of antigenic peptides.

With their prominently raised grooves they provide a means for blind people to traverse the city.

The minimization procedures used both Van der Waals potential for finding the best sterical fit of the ligand into the binding groove and the electrostatic potential provided by the MM94FF built-in SCULPT to assess the relative free energy of binding between the ligand and the target protein.