Sentence examples for binding functionality of the from inspiring English sources

This lack of binding functionality of the RGD sequences attached to the Ir OEP moiety could be due to a number of factors, including steric factors, the positive charge on the adjacent IrIII ion, or the hydrophobicity of the porphyrin core.

Thus, the binding functionalities of the 52+2 derivatives are retained.

Although the amide linker in the 4-phenylpiperazine class of D3R ligands has been previously deemed critical for high D3R affinity and selectivity, the 1,2,3-triazole moiety serves as a suitable bioisosteric replacement and maintains desired D3R-binding functionality of the compounds.

Our data clearly demonstrate that the purification process affects the integrity of the native quaternary structure of NoV VLPs and, subsequently, the receptor-binding functionality of the VLPs.

However, the disturbance of the testicular transcriptional network by YCMD is most likely a consequence of the lacking RNA-/DNA-binding functionality of the deleted genes which is important for any transcriptional network.

The resultant putative protein products of these AKAP7-like genes lack the AKAP7RI/ RII binding domain and likely the PKA binding functionality of derived AKAPs.

The binding functionalities of both mammalian and yeast derived preparations are gauged demonstrating the functional equivalence of the respective preparations.

Under milder conditions, more subtle conformation changes such as altered tertiary contacts can still affect binding functionality in the absence of proteolysis.

This offers the opportunity to explore if different projections of binding functionality result in preferential binding of target proteins.

In this work, the influence of GU base pairs on the effectivity of translation attenuation by miRNAs is assayed by mutating binding sites and comparing attenuation effectivity to wild type binding sites Introducing three GU base pairs into the mRNA/miRNA duplex did, with only minor changes to the binding energy, almost completely destroy the functionality of the binding site.

Such competitive factors only affect the binding efficiency, but do not influence the functionality of the binding.