Sentence examples for binding function suggesting that from inspiring English sources

Interestingly, all three structure-solved proteins have a putative DNA binding function, suggesting that YebC proteins may serve as a potential transcription factor.

Moreover, each protein has been co-opted from a prior DNA-binding function, suggesting that evolution to an RNA splicing factor is a recent event in evolutionary terms.

Moreover, mutating basic residues in the calmodulin binding site affected PIP binding and channel function, suggesting that PIPs interact directly with the calmodulin-binding site.

Mutations that disrupt Ca2+-binding to syt 7 abolish this function, suggesting that syt 7 functions as a Ca2+-sensor for replenishment.

Here we show that contrary to previous reports, predicted Fe(II)- and 2-OG-binding residues are required for Epe1 function, suggesting that Epe1 is a 2-OG/Fe(II -dependent dII -dependent

Interestingly, binding of imatinib to the kinase-defective tyrosine-mutant restored the NLS function, suggesting that the kinase domain conformation induced by imatinib-binding is critical to the re-activation of the NLS function.

Our current knowledge of Tpz1 protein structure and function suggests that K75 falls within the Pot1-binding domain [ 11].

Reports of U2A′ function suggest that its principal biochemical role is to increase the binding affinity of U2B″ for SLIV.

However, an N-terminal deletion mutant of Foxp3 was also incapable of performing these functions, suggesting that binding of further factors might be required [18].

These defects were efficiently rescued by not only wild-type mouse Bach1, but also its derivatives lacking the DNA binding domain, suggesting that the function of Bach1 in mitosis involves a transcription-independent mechanism.

In contrast, the 5-HT3B substitutionsitutions did not alter 5-HT function or granisetron binding, suggesting that neither the principal nor the complementary faces of this subunit bind ligand or activate the receptor.