Sentence examples for binding function of the from inspiring English sources

The binding function of the Hc domain is essential for BoNTs to bind the neuronal cell membrane, therefore, removal of the Hc domain results in a product that retains the endopeptidase activity of the LC but is non-toxic.

Thus, the PAS domain is not necessary for the E-box binding function of the Arnt homodimer.

Because helix-4 mutations disrupt the F-actin binding function of the FABD, these results show that F-actin binding per se is not required for the inhibition of the NLS function.

In addition, these data provide insight into the less characterized cys-domain and suggest an important functional role for a less conserved region of the cys-domain that is distinct from the RNA binding function of the highly conserved cysteine-rich motif.

Rather, the suspected RNA binding function of the C-terminal domain of yeast mtLeuRS (Labouesse, 1990) suggests that it functions by stabilizing the mutant tRNAs.

Further, the antibodies were chosen such that the antibody binding does not interfere with receptor binding function of the hemagglutinin on the virus.

The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane [ 78].

Thus, their appearance on a scaffoldin may serve to enhance the substrate-binding function of the dockerin- containing enzymes, which bind to this scaffoldin protein via its type-I cohesins.

We conclude that the membrane-binding function of the catalytically inert PTEN C2 domain influences cdc42/aPKC-dependent AM dynamics and gland formation in a highly relevant 3D CRC morphogenesis model system.

These results demonstrate that the mutation significantly impaired the carbohydrate-binding function of the B subunit.

Of these two mutations, H118 corresponds to H82 of D. deserti irrE according to sequence alignment, and is directly involved in the zinc-binding function of the N-terminal domain.