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2. The methyl-lysine-recognizing Agenet domains of FMRP may still needed for its neuronal function, though Alpatov et al. have elucidated that the replication stress defective FMRP mutants, which abolish its methylated histone binding function, do not alter AMPAR internalization.
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Indeed, c-Cbl facilitates internalization of EGFR through binding to CIN-85, and its function does not depend on the E3 ubiquitin ligase activity of c-Cbl [16].
As a control, an antibody that has been shown to block β1-integrin function did not affect laminin binding in wildtype and dystroglycan-deficient cells with or without LARGE overexpression (data not shown).
Hepatic function did not improve.
Renal function did not improve.
HP1 family members play key roles in the formation of repressed chromatin states through binding of H3K9me3 or H3K27me3, although their functions do not seem to be restricted to gene silencing.
We show the synthetic kinetochore functions do not depend on the DNA-binding components of the natural kinetochore but do require other kinetochore proteins.
We show the synthetic kinetochore's functions do not depend on the DNA-binding components of the natural kinetochore but do require other kinetochore proteins.
For energies higher than 6 eV, the optical functions do not depend on the film thickness, so the interactions of the photons are with tight-binding electrons.
Bodily functions do not embarrass her, either.
Some council functions don't ever change.
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CEO of Professional Science Editing for Scientists @ prosciediting.com