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As an example, phosphorylation at the Ser235, Ser404 and Thr50 sites may in fact promote microtubule binding, formation and stability at specific sites (38, 39).
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Conservation of the spatial binding organizations at the level of physico-chemical interactions is important for the formation and stability of protein-protein complexes as well as protein and drug design.
Current evidence based on Fhit mutants with impaired substrate binding (L25W and I10W/L25W mutants) or hydrolytic activity (H96D mutant) supports the notion that the formation and stability of the Fhit-Ap3A complex is crucial in growth inhibition and apoptosis [ 5- 7].
Greer, A. L. New horizons for glass formation and stability.
Formation and stability of impurity "snakes" in tokamak plasmas.
Landforms influenced soil formation and stability.
His publications include numerous papers on the formation and stability of black holes.
However, the contribution of triplet microtubules to mammalian centriole formation and stability is unknown.
Understanding the numerous factors that can affect biofilm formation and stability remain poorly understood.
Here, we describe a novel druggable and clinically relevant pathway regulating MYO10-positive filopodia formation and stability.
Wong, H. M., Stegle, O., Rodgers, S. & Huppert, J. L. A Toolbox for Predicting G-Quadruplex Formation and Stability.
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