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The NBS domains of two NBS-LRR proteins, tomato I2 and Mi-1, have been demonstrated to be able to bind and hydrolyze ATP [ 34] and the ATP binding form is the active configuration of the I2 protein [ 35], suggesting that the NBS domain functions as a molecular switch in signal transduction eliciting the defense response.
"The title of the agreement is yet to be decided but it will not affect its legally binding form".
The government favours a code of practice, which it talks up as a "tough and legally binding form of self-regulation".
We asked them to bring a court case against Hanover, or submit an alternative but binding form of legal resolution to test this issue.
Rowan Williams, who took office in 2002, decided that the solution to the problem was to produce some legally binding form of organisation that would be coherent enough for people to be thrown out of it.
America wanted more flexibility.The reduced warhead totals that must be reached by 2012 have been set down in legally binding form, as Mr Putin wanted.
Similar(29)
In the present study we examine how binding of tryptophan to the protein controls the ability of TRAP to bind RNA, apparently switching it from a non-RNA-binding form to a RNA-binding form.
The CRIB domain, which specifically binds to activated Rac (i.e., a GTP-binding form), was used to precipitate the activated Rac from cell lysates.
It can be also regularized on a 2D square lattice in the following tight-binding form: (1).
Given evidence for distinct signaling and adhesive forms of β-catenin in C. elegans, and Drosophila [5], [6], we sought to characterize molecular properties of the nuclear and cadherin-binding form of β-catenin using recently developed antibodies that recognize distinct phospho-forms of β-catenin.
The structural investigations of the TetR complexed with its signal molecule, tetracycline, in comparison with its DNA-binding form revealed that binding of the induce molecule would cause specific conformational changes in both the ligand binding pocket and the DNA-binding domain that result in release of the repressor from the operator, and thus allow transcription from the cognate promoter.
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