Sentence examples for binding for proper from inspiring English sources
Our in vitro and in vivo results provide evidence for the importance of direct TF-DNA binding for proper spatial rx2 expression in RSCs.
Coming challenges are to identify whether all of these P4-ATPase require a Cdc50 binding partner for proper functioning and whether they can interact with several Cdc50 proteins as shown for the Arabidopsis P4-ATPase ALA3 [26].
Here, Isw1a may function to help assemble/mature and properly space nucleosomes at these promoters to repress transcription, which then increases their reliance upon remodelers such as RSC and/or SWI/SNF to expose these binding sites for proper activation.
The antibiotic geldanamycin (GA) inhibits HSP90's ATP binding for its proper interaction with client proteins.
Characterisation of the RPELMAL G-actin inteRPELMAL G-actinrescence aninteractiond cell reporter-bysed assays validates the signifluorescencectin-binding residues for proper Manisotropyandon and regulation in vivo.
It stabilizes a conformation of apo-PP2Ac that facilitates metal chelation and ATP binding and hydrolysis, whereby the precise geometry of ATP binding at the active site is important for selectively enhanced binding of proper catalytic metal ions, which influences phosphatase specificity.
Intriguingly, we found that key residues in the dsRBD that are required for dsRNA binding are dispensable for proper functioning of Dcr1 in the RNAi pathway.
Import systems are specific to prokaryotic organisms and contain ABC and IM domains on separate polypeptide chains along with an extracytoplasmic binding protein (BP) for proper function.
Our results show that both the C-terminal tail and the WHD constitute a linker histone fold-binding domain and are necessary for proper binding and folding of the chromatin fibre.
Thus, calcium binding is a critical prerequisite for proper substrate binding.
For INO80, the Arp8 module is a DNA-binding sensor required for proper docking of the catalytic subunit and ATPase domain, which is quite distinct from how Arps regulate RSC and SWI/SNF through direct interaction with their ATPases domains12,34,35,36.
