Sentence examples for binding features of several from inspiring English sources
Co-crystallization studies with protein kinase A and other kinases have revealed binding features of several classes of protein kinase inhibitors.
Thus, these binding locations may represent an evolutionarily conserved structural feature of several viral polymerases that could be exploited for the development of small molecule therapeutics.
A prominent feature of several type of cancer is cachexia.
Hyperphosphorylated tau is a significant pathological feature of several dementias.
"...increases the GTPase activity and the rate of nucleotide binding of several purified GTP-binding regulatory proteins (G proteins) whose function is to couple cell-surface receptors to intracellular mediators".
To determine the structural features of inhibitor binding, the crystal structures of several compounds in complex with hCA II were determined.
Comparison of the HIV-1 TAR dynamical ensemble and ligand bound TAR conformations reveals that several features of the binding pocket and global conformation are dynamically preformed, providing support for adaptive recognition via a 'conformational selection' type mechanism.
Auditory object perception requires binding of elementary features of complex stimuli.
Our structural data highlight several features of the WDR5-binding cavity that can be exploited to design in greater potency and cell permeability.
A notable feature is the clustering of several of these positions around the receptor binding site (shown in green), the active site for binding with target cell sialic acid.
