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In the present paper we describe the novel and unexpected binding features of a highly specific and unusual dual inhibitor FII.
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Co-crystallization studies with protein kinase A and other kinases have revealed binding features of several classes of protein kinase inhibitors.
These results can be considered a proof-of-concept that the conformational preferences and binding features of isolated peptides derived from virus proteins could be used to mimic early stages of virus assembly.
Herein, we report structure-guided engineering of the lipid binding features of GLTP.
Homology model of Leishmania SIR2 shed new light on the ligand binding features of this enzyme.
The structural and binding features of bpzo in all related compounds have also been discussed.
Next, the complex of HLA-A2 and HBc141 149 was prepared for crystallization to characterize the binding features of HBc141 149.
The detailed structure activity relationships were analyzed and the binding features of compound 10b (IC50 5.38 μM) was predicted using CDOCKER program.
The binding features of reported PKCβII inhibitors, and high scoring hits were analyzed with the help of molecular docking studies.
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