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CTCF, a CCCTC binding factor, has a diverse role in genome regulation including transcriptional regulation, chromosome-boundary insulation, DNA replication, and chromatin packaging.
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The tef1 gene, a D-box enhancer element binding factor, has previously been reported to be light induced in zebrafish cells and larvae [25].
The gene encoding the SigU ECF sigma factor has a SigT binding motif in its promoter, suggesting it is directly regulated by SigT.
Not every transcription factor has a known binding motif, however.
AP-2γ, a DNA binding transcription factor, had a similar expression profile to OCT4 in germ cells of both the marmoset and human testis.
Splicing factors and 3′ UTR/poly(A) binding factors have been frequently studied, indicating their essential roles in RBP-based regulation.
Taken together, while a considerable number of putative bacterial binding factors have been described for C. jejuni, there is a large gap in our knowledge on the corresponding host cell receptors.
Several putative binding factors have been described for HBsAg, but their exact role in HBV attachment remains unclear [27] [29].
Multiple binding factors had to be analyzed simultaneously; however, results were reported independently.
However, among them, JMJD6, a histone arginine demethylase, and TERF2, a telomeric repeat-binding factor, have been re-annotated recently with supporting experimental evidence [49], [50].
This result suggests that Sp-DN prevents the binding of Sp factor having a repressive effect on REST promoter.
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